Case studies

Monobloc Cleanroom for Solid and Liquid Dose Medicine Production

Cubic Pharmaceuticals is the first life science company in the UK to achieve a patented design for its novel continuous granulation process for processing water insoluble Active Pharmaceutical Ingredients (APIs) by means of hot melt extrusion (HME). Cubic Pharmaceuticals required a cleanroom suite, for the manufacture of solid and liquid dose medicines, and appointed Angstrom Technology to build a 54m² monobloc cleanroom.

Pharmaceutical
Cleanroom Design & Build
UK
Monobloc Cleanroom for Solid and Liquid Dose Medicine Production at Cubic

Key facts

54m² monobloc cleanroom

GMP grade cleanroom

5 areas for mixing, production, cleaning and dispensing

Off-site constructed for an efficient installation

What did our client need?

Cubic Pharmaceuticals required a cleanroom suite, for the manufacture of solid and liquid dose medicines. Cubic Pharmaceuticals is the first life science company in the UK to achieve a patented design for its novel continuous granulation process for processing water insoluble Active Pharmaceutical Ingredients (APIs) by means of hot melt extrusion (HME).

With a unique continuous manufacturing process for processing most challenging APIs, its technology increases the solubility of ibuprofen to 80% within 15-20 minutes and 97% within 2 hours.

“We invented the manufacture of Ibuprofen through Hot Melt Extrusion, which is a world first”, says Saumil Bhatt, Cubic Pharmaceuticals. “We also use platform technology to manufacture another 30 different non-soluble molecules through Hot Dry Extruded Granulation.”

Monobloc Cleanroom for Solid and Liquid Dose Medicine Production at Cubic

How did we help our client?

The monobloc cleanroom suite encompasses 5 areas for mixing, production, cleaning and dispensing, plus a change area for operatives. It was off-site constructed for an efficient installation.

Monobloc Cleanroom for Solid and Liquid Dose Medicine Production at Cubic

How did our client benefit?

“This GMP grade cleanroom has transformed Cubic Pharmaceuticals to a Contract Research Organisation (CRO), allowing pharma companies to benefit from our technology breakthroughs,” says Saumil Bhatt, Cubic Pharmaceuticals.

Monobloc Cleanroom for Solid and Liquid Dose Medicine Production at Cubic

Monobloc Cleanroom for Solid and Liquid Dose Medicine Production at Cubic

 

 

 

This GMP grade cleanroom has transformed us to a Contract Research Organisation (CRO), allowing pharma companies to benefit from our technology breakthroughs.

We used Angstrom Technology because of the amount of projects they have delivered, the affordable cost and their track record of high quality work.

Cubic Pharmaceuticals
CEO
Custom built GMP cleanroom

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